Effects of Stone Dust Exposure on Some Liver and Kidney Related Serum Parameters of Stone Crush Plant Workers

Ikram Ilahi, Asghar Khan, Mehboob Ali, Ubaid Ullah, Jawad Ali, Murad Khan


In the present study the effects of stone dust exposure on liver and kidney related serum parameters were assessed in workers of stone crush plants in various localities of Swat and Dir (L) districts of Khyber Pakhtunkhwa, Pakistan. The liver and kidney related serum parameters included Glutamate Pyruvate Transaminase (GPT), Alkaline Phosphatase (ALP), bilirubin and creatinine. Blood samples were collected from 66 exposed workers and 66 unexposed persons (control). The mean values of liver related parameters i.e. serum GPT, ALP and bilirubin of workers were significantly higher than control persons (P<0.05). The mean value of kidney related parameter i.e. creatinine of workers   was significantly higher as compared to control persons (P<0.05).  From the present survey it was concluded that continuous exposure to stone dust can cause abnormal alterations in the normal levels of serum GPT, ALP, bilirubin and creatinine.

Full Text:


DOI: http://dx.doi.org/10.5296/jbls.v3i1.1961

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

To make sure that you can receive messages from us, please add the 'macrothink.org' domain to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', check your 'bulk mail' or 'junk mail' folders.

Copyright © Macrothink Institute   ISSN 2157-6076