This research is done in Makassar, in order to explain comprehension and interpretation of gender and implementation of the 5 Buginese man and wife as informants based on life-guidance, social relation, patriarchy perception, social behavior, and woman’s double role. This research uses qualitative method with case study and phenomenological. The informant’s is determined purposively, they are the 5 Buginese man and wife with double role case, whether those who are civil servants, entrepreneur, politician, or home industry actors. This research’s result shows that 5 cases of Buginese man and wife informants understand and interpret gender as agreement and conformity of man’s and woman’s function in taking the role based on cultural and religious value, which are siri’, pangaderreng, sipakatau, sipakalebbi, and teppe’, as included in life-guidance because those values become binding frame of man and wife in gender implementation. Gender equality implication with women’s double role in 5 Buginese man and wife as informants case are realized in the financial development, spiritual gift, motivation and achievement of themselves and family, because Buginese citizens on that case do not prohibit their wives to work and the religion is allowing wives to have 2 roles, but they need to keep siri’ , self esteem and also the agreement from the husband. Spending time at home with husband in the evening is less in quantity, but it is not in quality.