Effects of Occupational Exposure to Wood Smoke in Tandoor Occupants

Abstract

Exposure to wood smoke leads to mucosal irritation and physiological and neurological abnormalities in human.Blood samples along with histories were taken from 100(50Tandoor occupants and 50 controls) male individualsliving in the same locality. SYSMIX KX-21 (Japan) and Shimadzu Double Beam Spectrophotometer 1700 Pharma (Japan) were used for blood profiling and serum biochemistry. In workers, blood cholesterol was 131 ± 4.8 mg/dl, triglyceride was 125 ± 10mg/dl, and serum glutamate pyruvate transaminase level was 68 ± 2.4IU/L and glucose level was 113 ± 2.1 mg/dl. The total red blood cell count was 5.6 ± 0.035mill/cmm, hemoglobin level was15 ± 0.054mg/dl, hematocrit value was49 ± 0.22 mg/dl, mean corpuscular volume was 86 ± 0.22 fl,mean corpuscular hemoglobin was 31 ± 0.12 pg, mean corpuscular hemoglobin concentration was 35 ± 0.12gm/dl, neutrophils were 77 ± 0.50%, lymphocytes were 45 ± 1.0 %, eosinophilswere6.0 ± 0.14%, monocytes were 7.7 ± 0.19 %, total leukocyte count were 11014 ± 115/cmm, and platelets were235864 ± 5491 /cmm. In control group the blood cholesterol, triglyceride, serum glutamate pyruvate transaminase and glucose level was111 ± 2.4mg/dl,97 ± 1.5mg/dl, 28 ± 1.1IU/L and 101 ± 1.2 mg/dl respectively, while thetotal red blood cell count, hemoglobin level, hematocrit value, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobinconcentration, neutrophils, lymphocytes, eosinophils, monocytes, leukocyte, and platelets were4.3 ± 0.027mil/cmm, 12 ± 0.064 mg/dl, 38 ± 0.11mg/dl, 75 ± 0.30fl, 25 ± 0.37pg, 31 ± 0.11gm/dl, 56 ± 0.82%, 34 ± 1.0, 3.1 ± 0.20%, 4.2 ± 0.12%, 6573 ± 125, and 169162 ± 2454 /cmm respectively.The levels in both groups were statistically compared using t test and the p value was determined.The results showed that there was significant increase in blood biochemical parameters as well as in complete blood count in workers as compared to control and are therefore at more risk to heart, lungs and blood diseases.