Non-Specific Immune Response of Vanname Shrimp (Litopeaneus vanname) Induced by Chitosan as an Immunomodulator against IMNV (Infectious Myonecrosis Virus) Exposure

Abstract

Chitosan is one of polysaccharide derivatives commonly known as poly D-glucosamin-2 amino-2 dexoy-D-glucose, and glucosamine has a nearly similar chemical structure with β-glucan. It is capable of activating Prophenoloxidase (ProPO) to enhance immune system of shrimp. Chitosan is added to the food with treatment dose of 3 ml, 6 ml, 9 ml, and 12 ml. Then one negative control (not infected with IMNV) and one positive control (infected with IMNV). Shrimps are infected with IMNV through injection and THC, DHC, phagocytosis activity, super anionoxide and phenoloxidase (PO) are carefully observed. The most optimum result was obtained in the treatment of 3 ml Chitosan/kg food and the lowest result was found in the positive control.